Wendigo Skull

Effects

 * Grants a bone heart.
 * Grants a chance of converting any red hearts pickups into bone hearts instead.
 * Grants +40% damage, +20% tears, +10% speed, +10% shot speed, +5% range and +5% tears height.
 * Upon damage, all positive stats become negative, decreasing Isaac's stats until room is changed.

Synergies

 * Black Candle: Prevents changing stats upon damage.
 * Dull Razor: Negative stats are not triggered.

Trivia

 * Wendigo Skull is only recommended for players who play without taking much damage.
 * This item is basically an all-stats multiplier up for The Lost, since he is not able to take damage.